Skip to content
  • Product
  • How it Works
  • Clinical Evidence
  • For Clinicians
  • Product
  • How it Works
  • Clinical Evidence
  • For Clinicians
+1 844.475.7100
US United States
Europe Europe
Canada Canada
Other Other
  • Product
  • How it Works
  • Clinical Evidence
  • For Clinicians
  • Product
  • How it Works
  • Clinical Evidence
  • For Clinicians
+1 844.475.7100
US United States
Europe Europe
Canada Canada
Other Other
Migraine and Endometriosis
October 14, 2024

Migraine and Endometriosis

Around 43% of women have experienced a migraine attack at some point in their lives. Migraine disorder is one of the most common conditions worldwide and affects women more than men. Many women also have endometriosis, which is a chronic inflammatory condition. Roughly 10% of all reproduction-age women have endometriosis. While migraine and endometriosis may seem like they have nothing in common, researchers have found a link between the two conditions.

If you have endometriosis and migraine, it’s beneficial to understand both conditions and what connects them. It’s also good to know you’re not alone in your experience. In this article, you’ll learn more about the two disorders and how they’re related. We’ve also included some migraine management tips to help reduce migraine’s impact on your life.

  • What is migraine
  • What is endometriosis
  • Connection between migraine and endometriosis
  • Migraine management strategies

What is migraine?

While many people think that migraine is just a “bad headache,” migraineurs know it’s much more than that. Migraine is a complex neurological disorder that can affect your daily life. The disorder looks different for everyone, and headaches are only one of its symptoms. Other migraine symptoms include:

  • Pulsing head pain.
  • Nausea or vomiting.
  • Sensitivity to light and sound.
  • Dizziness.

Migraine attacks can affect your whole body and last as long as 72 hours. They occur in stages, starting with prodrome. Prodrome occurs up to 24 hours before an attack. During prodrome, you may experience symptoms like mood changes, difficulty concentrating and trouble sleeping. If you have migraine with aura, you may experience visual and auditory disturbances along with muscle weakness. During the attack, nausea and head pain reach their peak. However, it doesn’t end there — you can feel fatigued, stiff and distracted long after an attack ends.

Many things can trigger a migraine attack, including food, stress, dehydration, weather changes, hormones and lack of sleep.

Get Drug-Free Migraine Relief With CEFALY

90-day money back guarantee
FDA-Cleared
Financing available

What is endometriosis? 

Endometriosis is a chronic disease that affects women. It typically starts a few years after menstruation begins and can last until menopause. For this reason, the age range for endometriosis is usually 25 to 40 years old. The condition involves endometrium tissue — the uterine lining you shed during menstruation. When you have endometriosis, endometrium-like tissue grows outside the uterus, in places like the ovaries, fallopian tubes, outer uterus and pelvic cavity. In rare cases, it may grow on the bladder, intestines, cervix, stomach or diaphragm.

Endometrium-like tissue is hormone-sensitive. During the menstrual cycle, endometrium tissue is expelled from the uterus. However, endometrium-like tissue growing in other parts of the body can’t shed this way. As it builds up, it can become inflamed and cause scarring, adhesions and cysts. This can be extremely painful and even affect your ability to get pregnant.

Common symptoms of endometriosis include:

  • Painful menstrual cramps.
  • Pain during sex.
  • Heavy or irregular periods.
  • Abdominal pain.
  • Painful bowel movements.
  • Fatigue.

Research on migraine and endometriosis

While migraine isn’t a direct symptom of endometriosis, it is often present in women who live with the condition.

A few studies provide some insight into this phenomenon. Here are some of the most prominent findings:

  • Women with endometriosis are more likely to have migraine than those who don’t have endometriosis.
  • For women with migraine and endometriosis, migraine often gets worse closer to or during menstruation.
  • Dysmenorrhoea — painful menstrual periods — is more common for women with both conditions.
  • Women with migraine are 4.6 times more likely to have severe endometriosis.
  • Migraine headache symptoms usually start years before individuals get an endometriosis diagnosis.
Women with migraine are 4.6 times more likely to have severe endometriosis.

The connection between migraine and endometriosis

From research findings, it’s clear that comorbidity — the existence of two conditions in one individual — is high with migraine and endometriosis. So, while there is no evidence to suggest endometriosis causes migraine, the two conditions are often associated with one another. Researchers believe that menstrual hormones may play a significant role.

Nearly two out of three women with migraine report that menstruation is a trigger. The reason for this is the change in hormone levels throughout the menstrual cycle. As you get closer to menstruation, your estrogen and progesterone levels drop. When this happens, you’re more likely to have a migraine attack. Anything that results in hormonal fluctuations can impact migraine attacks. Pregnancy, fertility treatments, menopause and certain medications can all affect your hormones and experience with migraine.

Endometriosis is also linked to menstruation. During their period, women with endometriosis experience debilitating cramps. Other symptoms may also flare up around this time. For people with both endometriosis and migraine, two types of migraine — pure menstrual and menstrually related migraine — were the most common. Pure menstrual migraine attacks happen exclusively during menstruation, while menstrually-related migraine attacks happen more frequently at that time. Unfortunately, this means that both migraine headaches and endometriosis pain are likely to occur close together.

Try CEFALY to Prevent & Relieve Migraine Pain

Management strategies for people with migraine and endometriosis

Managing migraine when you live with endometriosis can require an experimental mindset. Some treatments may work better for you than others, so try multiple approaches. The following are a few strategies you can add to your endometriosis migraine management plan:

  • Medication: Over-the-counter painkillers — like ibuprofen and acetaminophen — can help relieve both migraine and endometriosis pain. If your migraine pain is particularly bad, you may need a prescription for nonsteroidal anti-inflammatory drugs (NSAIDs) or triptans.
  • Hormone therapy: If menstruation is a trigger for you, hormone therapy may help. Your doctor may prescribe a combined oral contraceptive in the form of pills or patches. Hormone therapy can regulate your hormone levels and alleviate migraine pain.
  • Avoid triggers: It’s easier said than done, but staying clear of your migraine triggers makes a big difference. While you can’t control some triggers, others are relatively simple to adjust. You can eat healthier foods, drink plenty of water and get enough sleep.
  • Acupuncture: A traditional Chinese medicine called acupuncture may reduce the frequency of migraine attacks. The procedure involves inserting needles into pressure points into the body, which helps both migraine head pain and endometriosis.
  • Exercise: Consistent light exercise can reduce stress, moderate estrogen levels and lessen inflammation, making it a good treatment option for people with migraine disorder and endometriosis.
  • Neuromodulation: Neuromodulation technology uses electrical stimulation to alleviate chronic pain. CEFALY devices directly stimulate the trigeminal nerve, which is the primary pathway for migraine pain.

Have more migraine-free days with CEFALY

CEFALY is the #1 FDA-cleared, drug-free migraine treatment device. It offers two treatment modes — ACUTE and PREVENT. The ACUTE mode is best for when you feel the first signs of a migraine attack. It’ll interrupt the pain signals to make your migraine headache and other symptoms fade away. The PREVENT mode helps desensitize the trigeminal nerve, which can lead to fewer attacks with consistent daily use.

CEFALY is clinically proven to alleviate migraine. In just one hour, 63% of study participants said the ACUTE treatment mode reduced their headache pain by half or more. 

Try a CEFALY device for 90 days with a money-back guarantee!

Have more migraine-free days with CEFALY

Related Posts:

  • FAQ
    FAQ
  • Explore-the-Connection-Migraine-and-PTSD
    Explore the Connection: PTSD and Migraine 
  • Anxiety
    Migraine and Anxiety: How Are They Linked?
  • aura is a set of symptoms that about 25-30 % of migraine patients experience
    What Type Of Migraine Do I Have?
  • build exercise routine
    Why Do I Get a Migraine After Exercise — and How Do…
  • migraine and adhd
    Migraine and ADHD
← Previous Post
Next Post →

Search the CEFALY Blog

Recent Posts

  • A mom with short brown hair hugs her son while wearing the CEFALY migraine device "CEFALY Gave Me My Life Back": Camille's Search for a Drug-Free Migraine Treatment
  • Episodic migraine vs chronic migraine What Patients Need to Know About Episodic Migraine vs. Chronic Migraine
  • A woman smiles while holding a model of the brain “That’s When I Realized: I Have Migraine.” Beth’s Empowerment Story
  • A glossy black CEFALY migraine device on a blue background The CEFALY Technology Origin Story: 20+ Years of Migraine Innovation
  • Unable to Tolerate Migraine Medication, She Turned to CEFALY: Lori's Migraine Story

Categories

  • CeCe App
  • CEFALY Education
  • CEFALY Journey
  • Clinician's Corner
  • Customer Testimonials
  • Healthcare
  • Living with Migraine
  • Men's Health
  • Mental Health
  • Migraine 101
  • Migraine Info
  • Migraine Stories
  • Migraine Triggers
  • Seasonal Triggers
  • Veterans
  • Women's Health

Latest Posts

Essential Oils for Migraine Headaches
CEFALY Education

The Essential Guide To Medical Devices For Migraine

May 24, 2024
Read More →
A mom with short brown hair hugs her son while wearing the CEFALY migraine device
CEFALY Journey

“CEFALY Gave Me My Life Back”: Camille’s Search for a Drug-Free Migraine Treatment

Discouraged by her experience with medications, Camille began building a toolkit of non-pharmacologic migraine treatments. Find out what…

January 27, 2026
Read More →
Episodic migraine vs chronic migraine
Migraine Stories

What Patients Need to Know About Episodic Migraine vs. Chronic Migraine

While official definitions classify episodic migraine as fewer than 15 headache days per month and chronic migraine as…

January 2, 2026
Read More →
  • Cefaly App
  • Find a Provider
  • For Clinicians
  • Cefaly App
  • Find a Provider
  • For Clinicians
SUPPORT
Schedule Coaching
FAQ
Electrodes
CEFALY App
Find a Certified Provider
Quick Start Guide
Returns & Warranty
Contact Us
PROFESSIONAL
For Clinicians
Clinical Studies
INSURANCE & BENEFITS
HSA/FSA Eligible
COMPANY
About Us
Reviews
Careers
Affiliates
Influencers

Privacy Policy

Terms of Service

Return Policy

Cookie Policy

Do Not Sell My Personal Information

The CEFALY Migraine Relief app, CEFALY Connected device, and coaching services are not yet available in the EU.
© 2026 Cefaly. All Rights Reserved.

Region change detected

Checking your region...